| Santana vs Reina | 20–35 | 36.36% |
| Santana vs Jin | 28–26 | 51.85% |
| Santana vs Lidia | 18–34 | 34.62% |
| Santana vs Kazuya | 24–27 | 47.06% |
| Santana vs King | 15–28 | 34.88% |
| Santana vs Hwoarang | 15–20 | 42.86% |
| Santana vs Law | 14–17 | 45.16% |
| Santana vs Yoshimitsu | 11–19 | 36.67% |
| Santana vs Heihachi | 11–17 | 39.29% |
| Santana vs Steve | 10–16 | 38.46% |
| Santana vs Nina | 9–17 | 34.62% |
| Santana vs Asuka | 13–12 | 52.00% |
| Santana vs Jun | 8–17 | 32.00% |
| Santana vs Bryan | 13–11 | 54.17% |
| Santana vs Dragunov | 11–13 | 45.83% |
| Santana vs Eddy | 5–17 | 22.73% |
| Santana vs Paul | 8–13 | 38.10% |
| Santana vs Azucena | 9–10 | 47.37% |
| Santana vs Lars | 9–9 | 50.00% |
| Santana vs Lili | 4–11 | 26.67% |
| Santana vs Xiaoyu | 3–11 | 21.43% |
| Santana vs Jack-8 | 5–8 | 38.46% |
| Santana vs Claudio | 5–8 | 38.46% |
| Santana vs Lee | 4–8 | 33.33% |
| Santana vs Victor | 2–10 | 16.67% |
| Santana vs Feng | 6–5 | 54.55% |
| Santana vs Alisa | 3–7 | 30.00% |
| Santana vs Kuma | 5–5 | 50.00% |
| Santana vs Devil Jin | 3–5 | 37.50% |
| Santana vs Leroy | 2–6 | 25.00% |
| Santana vs Raven | 5–2 | 71.43% |
| Santana vs Panda | 0–4 | 0.00% |
| Santana vs Leo | 0–3 | 0.00% |
| Santana vs Shaheen | 2–1 | 66.67% |
| Santana vs Zafina | 0–2 | 0.00% |
Limitations
This data is often requested to give insight into which characters you have more trouble with than others, but it is not particularly helpful for that. The main issue is that it is heavily skewed by how strong the opponents you play are.
For example, this data suggests my worst matchup is clearly vs Reina, but that's just because most of those games are vs Yagami.
There is a way to account for this being worked on. The central idea is to assign each matchup a rating vs you which adjusts based on the result, much like the regular rating but also based on the rating of each player. With this, it would give a better summary of how well you perform vs each character.
In the meantime, this page is here to present the data as requested.