| Vayne vs Jin | 17–23 | 42.50% |
| Vayne vs King | 19–16 | 54.29% |
| Vayne vs Kazuya | 24–11 | 68.57% |
| Vayne vs Dragunov | 12–23 | 34.29% |
| Vayne vs Law | 20–14 | 58.82% |
| Vayne vs Hwoarang | 21–11 | 65.62% |
| Vayne vs Lili | 16–15 | 51.61% |
| Vayne vs Steve | 15–15 | 50.00% |
| Vayne vs Victor | 18–8 | 69.23% |
| Vayne vs Nina | 11–13 | 45.83% |
| Vayne vs Jun | 12–12 | 50.00% |
| Vayne vs Bryan | 13–10 | 56.52% |
| Vayne vs Reina | 13–10 | 56.52% |
| Vayne vs Heihachi | 12–10 | 54.55% |
| Vayne vs Paul | 11–10 | 52.38% |
| Vayne vs Xiaoyu | 8–12 | 40.00% |
| Vayne vs Jack-8 | 10–10 | 50.00% |
| Vayne vs Asuka | 10–10 | 50.00% |
| Vayne vs Lee | 8–12 | 40.00% |
| Vayne vs Eddy | 9–7 | 56.25% |
| Vayne vs Clive | 3–13 | 18.75% |
| Vayne vs Leo | 12–3 | 80.00% |
| Vayne vs Zafina | 11–4 | 73.33% |
| Vayne vs Alisa | 10–4 | 71.43% |
| Vayne vs Devil Jin | 7–5 | 58.33% |
| Vayne vs Kuma | 7–4 | 63.64% |
| Vayne vs Raven | 5–6 | 45.45% |
| Vayne vs Azucena | 5–4 | 55.56% |
| Vayne vs Lars | 7–1 | 87.50% |
| Vayne vs Shaheen | 4–4 | 50.00% |
| Vayne vs Leroy | 4–4 | 50.00% |
| Vayne vs Feng | 6–1 | 85.71% |
| Vayne vs Lidia | 3–2 | 60.00% |
| Vayne vs Yoshimitsu | 3–1 | 75.00% |
| Vayne vs Claudio | 2–1 | 66.67% |
| Vayne vs Panda | 2–1 | 66.67% |
| Vayne vs Anna | 0–2 | 0.00% |
Limitations
This data is often requested to give insight into which characters you have more trouble with than others, but it is not particularly helpful for that. The main issue is that it is heavily skewed by how strong the opponents you play are.
For example, this data suggests my worst matchup is clearly vs Reina, but that's just because most of those games are vs Yagami.
There is a way to account for this being worked on. The central idea is to assign each matchup a rating vs you which adjusts based on the result, much like the regular rating but also based on the rating of each player. With this, it would give a better summary of how well you perform vs each character.
In the meantime, this page is here to present the data as requested.